Kojic acid repurposing as a pancreatic lipase inhibitor and the optimization of its production from a local Aspergillus oryzae soil isolate

Kojic acid repurposing as a pancreatic lipase inhibitor and the optimization of its production from a local Aspergillus oryzae soil isolate

Abstract Background Obesity and its related diseases are increasing worldwide. One of the best therapeutic strategies for obesity management is through the inhibition of pancreatic lipase (PL) enzyme. So far orlistat is the only FDA approved PL inhibitor, but with unpleasant side effects. New effica...

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Bibliographic Details
Main Authors: Sarah Mohamed El-Korany, Omneya Mohamed Helmy, Ali Mahmoud El-Halawany, Yasser El-Mohammadi Ragab, Hamdallah Hafez Zedan
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Biotechnology
Subjects:
Anti-obesity
Pancreatic lipase inhibitor
Soil fungi
Aspergillus oryzae
Kojic acid
Orlistat
Online Access:http://link.springer.com/article/10.1186/s12896-020-00644-9

Internet

http://link.springer.com/article/10.1186/s12896-020-00644-9

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