Inverse probability weighting to estimate causal effect of a singular phase in a multiphase randomized clinical trial for multiple myeloma

Abstract Background Randomization procedure in randomized controlled trials (RCTs) permits an unbiased estimation of causal effects. However, in clinical practice, differential compliance between arms may cause a strong violation of randomization balance and biased treatment effect among those who c...

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Bibliographic Details
Main Authors: Annalisa Pezzi, Michele Cavo, Annibale Biggeri, Elena Zamagni, Oriana Nanni
Format: Article
Language:English
Published: BMC 2016-11-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-016-0253-9