Bone-marrow mononuclear cells and acellular human amniotic membrane improve global cardiac function without inhibition of the NLRP3 Inflammasome in a rat model of heart failure

Bone-marrow mononuclear cells and acellular human amniotic membrane improve global cardiac function without inhibition of the NLRP3 Inflammasome in a rat model of heart failure

Abstract Recent studies have suggested that therapies with stem cells and amniotic membrane can modulate the inflammation following an ischemic injury in the heart. This study evaluated the effects of bone-marrow mononuclear cells (BMMC) and acellular human amniotic membrane (AHAM) on cardiac functi...

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Main Authors: ALINE L. TAKEJIMA, PAULO ANDRÉ B. MACHADO-JÚNIOR, GUSTAVO G. BLUME, ROSSANA BAGGIO SIMEONI, JULIO CESAR FRANCISCO, MURILO S. TONIAL, LUIS FELIPE B. MARQUEZE, LUCIA NORONHA, MARCIA OLANDOSKI, ELTYEB ABDELWAHID, KATHERINE A.T. DE CARVALHO, RICARDO A. PINHO, LUIZ CÉSAR GUARITA-SOUZA
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2024-03-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
heart failure
Bone-marrow mononuclear cells
Amniotic membrane
NLRP3 inflammasome
oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000100801&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000100801&tlng=en

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