C11-hydroxy and C11-oxo C<sub>19</sub> and C<sub>21</sub> Steroids: Pre-Receptor Regulation and Interaction with Androgen and Progesterone Steroid Receptors

C11-hydroxy and C11-oxo C<sub>19</sub> and C<sub>21</sub> Steroids: Pre-Receptor Regulation and Interaction with Androgen and Progesterone Steroid Receptors

C11-oxy C<sub>19</sub> and C11-oxy C<sub>21</sub> steroids have been identified as novel steroids but their function remains unclear. This study aimed to investigate the pre-receptor regulation of C11-oxy steroids by 11β-hydroxysteroid dehydrogenase (11βHSD) interconversion a...

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Bibliographic Details
Main Authors: Rachelle Gent, Desmaré Van Rooyen, Stephen L. Atkin, Amanda C. Swart
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
11β-hydroxysteroid dehydrogenase (HSD11B)
11β-hydroxyandrostenedione (11OHA4)
11β-hydroxyprogesterone (11OHP4)
adrenal steroidogenesis
androgen receptor (AR)
castration-resistant prostate cancer (CRPC)
Online Access:https://www.mdpi.com/1422-0067/25/1/101

Internet

https://www.mdpi.com/1422-0067/25/1/101

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