On the Reversible and Irreversible Inhibition of Rhodesain by Curcumin

Previously, it was suggested that the natural compound curcumin is an irreversible inhibitor of rhodesain, the major lysosomal cysteine protease of the protozoan parasite <i>Trypanosoma brucei</i>. The suggestion was based on a time-dependent inhibition of the enzyme by curcumin and a la...

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Bibliographic Details
Main Author: Dietmar Steverding
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/1/143