Gut microbiota is associated with bone mineral density: an observational and genome-wide environmental interaction analysis in the UK Biobank cohort

Gut microbiota is associated with bone mineral density: an observational and genome-wide environmental interaction analysis in the UK Biobank cohort

Aims: Despite the interest in the association of gut microbiota with bone health, limited population-based studies of gut microbiota and bone mineral density (BMD) have been made. Our aim is to explore the possible association between gut microbiota and BMD. Methods: A total of 3,321 independent loc...

Full description

Bibliographic Details
Main Authors: Bolun Cheng, Yan Wen, Xuena Yang, Shiqiang Cheng, Li Liu, Xiaomeng Chu, Jing Ye, Chujun Liang, Yao Yao, Yumeng Jia, Feng Zhang
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-11-01
Series:Bone & Joint Research
Subjects:
gut microbiota
bone mineral density
polygenic risk score
bone mineral density (bmd)
femur
single-nucleotide polymorphisms (snps)
linear regression models
osteoporosis
osteoblasts
bone formation
macrophages
bone density loss
bone metabolism
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.1011.BJR-2021-0181.R1

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.1011.BJR-2021-0181.R1

Similar Items