EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System

ABSTRACT Pathogenic mycobacteria encounter multiple environments during macrophage infection. Temporally, the bacteria are engulfed into the phagosome, lyse the phagosomal membrane, and interact with the cytosol before spreading to another cell. Virulence factors secreted by the mycobacterial ESX-1...

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Bibliographic Details
Main Authors: Kevin G. Sanchez, Micah J. Ferrell, Alexandra E. Chirakos, Kathleen R. Nicholson, Robert B. Abramovitch, Matthew M. Champion, Patricia A. Champion
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02807-19