The selection of software and database for metagenomics sequence analysis impacts the outcome of microbial profiling and pathogen detection.

Shotgun metagenomic sequencing analysis is widely used for microbial profiling of biological specimens and pathogen detection. However, very little is known about the technical biases caused by the choice of analysis software and databases on the biological specimen. In this study, we evaluated diff...

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Bibliographic Details
Main Authors: Ruijie Xu, Sreekumari Rajeev, Liliana C M Salvador
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0284031