Evaluation of the beneficial effects of a GABA-based product containing Melissa officinalis on post-inflammatory irritable bowel syndrome: a preclinical study

Evaluation of the beneficial effects of a GABA-based product containing Melissa officinalis on post-inflammatory irritable bowel syndrome: a preclinical study

IntroductionVisceral pain represents the most common digestive issue, frequently resulting from long-term inflammation, such as inflammatory bowel diseases. The lack of effective drugs prompted search of new therapeutic approaches. In this regard, gamma-aminobutyric acid (GABA) and Melissa officinal...

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Bibliographic Details
Main Authors: Elena Lucarini, Laura Benvenuti, Clelia Di Salvo, Vanessa D’Antongiovanni, Carolina Pellegrini, Giulia Valdiserra, Clara Ciampi, Luca Antonioli, Christian Lambiase, Lorenzo Cancelli, Antonio Grosso, Lorenzo Di Cesare Mannelli, Massimo Bellini, Carla Ghelardini, Matteo Fornai
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Pharmacology
Subjects:
irritable bowel syndrome
colitis
GABA
Melissa officinalis
abdominal pain
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1466824/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1466824/full

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