Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish

The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share specific substrates. Mib1 is known to play essential roles in Notch signalling by ubiquitinating Notch ligands in vivo. Conversely, the functions of Mib2 in vivo are not ful...

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Bibliographic Details
Main Authors: Shohei Mikami, Mizuki Nakaura, Atsuo Kawahara, Takamasa Mizoguchi, Motoyuki Itoh
Format: Article
Language:English
Published: The Company of Biologists 2015-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/4/11/1576