The Role of Hormonal Replacement Therapy in BRCA Mutated Patients: Lights and Shadows

All cancers develop as a result of mutations in genes. DNA damage induces genomic instability and subsequently increases susceptibility to tumorigenesis. Women who carry mutations of BRCA 1 and BRCA2 genes have an augmented risk of breast and ovarian cancer and a markedly augmented probability of dy...

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Bibliographic Details
Main Authors: Vera Loizzi, Miriam Dellino, Marco Cerbone, Francesca Arezzo, Gerardo Cazzato, Gianluca Raffaello Damiani, Vincenzo Pinto, Erica Silvestris, Anila Kardhashi, Ettore Cicinelli, Eliano Cascardi, Gennaro Cormio
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/1/764