Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum

Abstract Background Asthma is a heterogeneous disease and understanding this heterogeneity will enable the realisation of precision medicine. We sought to compare the sputum and serum inflammatory profiles in moderate-to-severe asthma during stable disease and exacerbation events. Methods We recruit...

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Bibliographic Details
Main Authors: Michael A. Ghebre, Pee Hwee Pang, Dhananjay Desai, Beverley Hargadon, Chris Newby, Joanne Woods, Laura Rapley, Suzanne E. Cohen, Athula Herath, Erol A. Gaillard, Richard D. May, Chris E. Brightling
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12890-019-0906-7