Efficient deformation mechanisms enable invasive cancer cells to migrate faster in 3D collagen networks

Abstract Cancer cell migration is a widely studied topic but has been very often limited to two dimensional motion on various substrates. Indeed, less is known about cancer cell migration in 3D fibrous-extracellular matrix (ECM) including variations of the microenvironment. Here we used 3D time laps...

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Bibliographic Details
Main Authors: Laure Laforgue, Arnold Fertin, Yves Usson, Claude Verdier, Valérie M. Laurent
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11581-2