Renoprotective Effects of Melatonin in Young Spontaneously Hypertensive Rats with L-NAME

Renoprotective Effects of Melatonin in Young Spontaneously Hypertensive Rats with L-NAME

Nitric oxide (NO) deficiency occurs in humans and animals with hypertension and chronic kidney disease (CKD). An inhibitor of NO synthase, NG-nitro-l-arginine methyl ester (L-NAME) exacerbates kidney damage in the adult spontaneously hypertensive rat (SHR). We examined whether L-NAME exacerbated hyp...

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Bibliographic Details
Main Authors: Ming-Chou Cheng, Ting-Hsin Wu, Li-Tung Huang, You-Lin Tain
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Pediatrics and Neonatology
Subjects:
asymmetric dimethylarginine
hypertension
kidney disease
melatonin
nitric oxide
oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957213001794

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http://www.sciencedirect.com/science/article/pii/S1875957213001794

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