LNO3 AND L3 Are Associated With Antiproliferative And Pro-Apoptotic Action In Hepatoma Cells

LNO3 AND L3 Are Associated With Antiproliferative And Pro-Apoptotic Action In Hepatoma Cells

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Abstract The identification of antitumoral substances is the focus of intense biomedical research. Two structural analogues of thalidomide, LNO3 and L3, are two synthetic compounds that might possess such antitumor properties. We evaluated the toxicological effects of these substances, including cyt...

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Bibliographic Details
Main Authors: Leonardo Campos Zanelatto, Patrícia Benites Gonçalves da Silva, Daniele Sartori, Carolina Panis, Sandra Lepri, Ângelo de Fátima, Mário Sérgio Mantovani
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2016-06-01
Series:Genetics and Molecular Biology
Subjects:
thalidomide analogues
antiproliferative activity
cytotoxicity
free radicals
apoptosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000200270&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000200270&tlng=en

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