Genetics of Ankylosing Spondylitis—Focusing on the Ethnic Difference Between East Asia and Europe

Ankylosing spondylitis (AS) is a common, highly heritable inflammatory arthritis affecting the mainly axial joints in both East Asia and Europe. To date, the pathogenesis of AS is still unknown, although we know that genetics play a vital role in it. The HLA-B27 allele is found in over 85% of AS pat...

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Bibliographic Details
Main Authors: Xin Wu, Geng Wang, Luding Zhang, Huji Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.671682/full