Tyrosine kinase mutations of JAK2 are rare events in AML but influence prognosis of patients with CBF-leukemias

We investigated a large number of acute myeloid leukemia (AML) samples (n=959) for the presence of the JAK2 V617F mutation. We found a low incidence of the mutation in these AML samples (1%). JAK2 V617F mutations clustered in AML samples with an aberrant karyotype (p

Bibliographic Details
Main Authors: Thomas Illmer, Markus Schaich, Gerhard Ehninger, Christian Thiede
Format: Article
Language:English
Published: Ferrata Storti Foundation 2007-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/4295