REV, a BRET-based sensor of ERK activity

REV, a BRET-based sensor of ERK activity

Networks of signaling molecules are activated in response to environmental changes. How are these signaling networks dynamically integrated in space and time to process particular information? To tackle this issue, biosensors of single signaling pathways have been engineered. Bioluminescence resonan...

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Bibliographic Details
Main Authors: Chanjuan eXu, Marion ePeter, nathalie ebouquier, vincent eollendorff, Ignacio eVillamil, Jianfeng eLiu, Laurent eFagni, Julie ePerroy
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Endocrinology
Subjects:
biosensor
Bioluminescence resonance energy transfer (BRET)
BRET imaging
Fluorescence-lifetime imaging microscopy (FLIM)
Extracellular signal-regulated kinases (ERK)
spatio-temporal signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00095/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00095/full

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