Bioreactor analyses of tissue ingrowth, ongrowth and remodelling around implants: An alternative to live animal testing

Bioreactor analyses of tissue ingrowth, ongrowth and remodelling around implants: An alternative to live animal testing

Introduction: Preclinical assessment of bone remodelling onto, into or around novel implant technologies is underpinned by a large live animal testing burden. The aim of this study was to explore whether a lab-based bioreactor model could provide similar insight.Method: Twelve ex vivo trabecular bon...

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Bibliographic Details
Main Authors: Nupur Kohli, Konstantinos Theodoridis, Thomas A. G. Hall, Inigo Sanz-Pena, David C. A. Gaboriau, Richard J. van Arkel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
bone
mineralisation
osseointegration
preclinical
fixation
additive manufacturing
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1054391/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1054391/full

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