Qingfei mixture mitigates immunosuppression of tumor microenvironment in non-small cell lung cancer by blocking stat1/Ido1-mediated tryptophan-kynurenine pathway

Programmed death-1 (PD-1) acts as a T cell checkpoint and is important in controlling T cell exhaustion. Blocking the intercommunication across PD-1 and PD-L1 is promising for advanced lung cancer treatment. However, the response rate requires being strengthened. This study aimed to determine whethe...

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Bibliographic Details
Main Authors: Zhuo Chen, Yu-Heng Ding, Lan Shao, Xu-Ming Ji, Xiang Qian, Ai-Qin Zhang
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024082914