CRISPR-Cas12a: Functional overview and applications

Prokaryotes have developed an adaptive immune system called Clustered regularly interspaced short palindromic repeats (CRISPR) to combat attacks by foreign mobile genetic elements (MGEs) such as plasmids and phages. In the past decade, the widely characterized CRISPR-Cas9 enzyme has been redesigned...

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Bibliographic Details
Main Authors: Bijoya Paul, Guillermo Montoya
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Biomedical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417019305050