In vitro inhibition of angiogenesis by antibodies directed against the 37kDa/67kDa laminin receptor.

The 37kDa/67kDa laminin receptor (LRP/LR) is a central receptor mediating interactions between tumour cells and the basement membrane and is thereby a key player in adhesion and invasion, essential processes in metastatic cancer. To affect continued tumour growth, tumours induce angiogenesis for the...

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Bibliographic Details
Main Authors: Raksha Khusal, Bianca Da Costa Dias, Kiashanee Moodley, Clement Penny, Uwe Reusch, Stefan Knackmuss, Melvyn Little, Stefan F T Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3595224?pdf=render