Regnase-2 inhibits glioblastoma cell proliferation

Abstract Regnase-2 (Reg-2/MCPIP2/ZC3H12B) is uniquely expressed at a high level in the healthy brain and down-regulated in samples from patients with glioma, reaching the lowest level in high-grade glioblastoma multiforme (GBM). This RNase is involved in the regulation of neuroinflammation through t...

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Bibliographic Details
Main Authors: Weronika Sowinska, Mateusz Wawro, Jakub Kochan, Aleksandra Solecka, Jarosław Polak, Borys Kwinta, Aneta Kasza
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51809-x