Spatial Distribution of Intracellular Ion Concentrations in Aggregate‐Forming HeLa Cells Analyzed by μ‐XRF Imaging

Spatial Distribution of Intracellular Ion Concentrations in Aggregate‐Forming HeLa Cells Analyzed by μ‐XRF Imaging

Abstract Protein aggregation is a hallmark of several severe neurodegenerative disorders such as Huntington's, Parkinson's, or Alzheimer's disease. Metal ions play a profound role in protein aggregation and altered metal‐ion homeostasis is associated with disease progression. Here we...

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Bibliographic Details
Main Authors: Andreas Gräfenstein, Dr. Christoph Rumancev, Roland Pollak, Benjamin Hämisch, Vanessa Galbierz, Dr. Walter H. Schroeder, Dr. Jan Garrevoet, Dr. Gerald Falkenberg, Dr. Tobias Vöpel, Prof. Dr. Klaus Huber, Prof. Dr. Simon Ebbinghaus, Prof. Dr. Axel Rosenhahn
Format: Article
Language:English
Published: Wiley-VCH 2022-04-01
Series:ChemistryOpen
Subjects:
huntingtin
potassium
pseudoisocyanine chloride
X-ray fluorescence
zinc
Online Access:https://doi.org/10.1002/open.202200024

Internet

https://doi.org/10.1002/open.202200024

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