A novel ΔNp63-dependent immune mechanism improves prognosis of HPV-related head and neck cancer

A novel ΔNp63-dependent immune mechanism improves prognosis of HPV-related head and neck cancer

BackgroundDeconvoluting the heterogenous prognosis of Human Papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OSCC) is crucial for enhancing patient care, given its rapidly increasing incidence in western countries and the adverse side effects of OSCC treatments.MethodsTranscriptom...

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Bibliographic Details
Main Authors: Jana Mourtada, Christelle Lony, Anaïs Nicol, Justine De Azevedo, Cyril Bour, Christine Macabre, Patrick Roncarati, Sonia Ledrappier, Philippe Schultz, Christian Borel, Mickaël Burgy, Bohdan Wasylyk, Georg Mellitzer, Michaël Herfs, Christian Gaiddon, Alain C. Jung
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
ΔNp63
immune response
human papillomavirus
oropharyngeal squamous cell carcinoma
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1264093/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1264093/full

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