Angled Insertion of Microneedles for Targeted Antigen Delivery to the Epidermis

Angled Insertion of Microneedles for Targeted Antigen Delivery to the Epidermis

Peanut and tree nut allergies account for most food-induced anaphylactic events. The standard allergy immunotherapy approach involves subcutaneous injection, which is challenging because severe adverse reactions can occur when antigens spread systemically. Allergen localization within the epidermis...

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Bibliographic Details
Main Authors: Rohan Murty, Abishek Sankaranarayanan, Isabella I. Bowland, Juan Mena-Lapaix, Mark R. Prausnitz
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
coated microneedle patch
targeted drug delivery
skin epidermis
allergy immunotherapy
peanut protein
optical coherence tomography
Online Access:https://www.mdpi.com/1999-4923/14/2/347

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https://www.mdpi.com/1999-4923/14/2/347

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