Therapeutic Potential of Targeting Periostin in the Treatment of Graves’ Orbitopathy

Periostin is a matricellular protein that is ubiquitously expressed in normal human tissues and is involved in pathologic mechanism of chronic inflammatory and fibrotic disease. In this study we investigate periostin in the pathogenesis of Graves’ orbitopathy (GO) using human orbital adipose tissue...

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Bibliographic Details
Main Authors: Sun Young Jang, Jinjoo Kim, Jung Tak Park, Catherine Y. Liu, Bobby S. Korn, Don O. Kikkawa, Eun Jig Lee, Jin Sook Yoon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.900791/full