Beneficial effects of certain phosphodiesterase inhibitors on diabetes mellitus in rats

The present study is conducted to investigate the possible antidiabetic effect of certain phosphodiesterase inhibitors. Diabetes mellitus was induced in 18 h-fasted male wistar albino rats by intraperitoneal injection of streptozotocin (STZ) in a single dose (50 mg/kg). Gliclazide (Glcl) as a refere...

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Bibliographic Details
Main Authors: Mostafa El Sayed El Sayed, Nehad Eid, Ahmed Seif El Din Kamel
Format: Article
Language:English
Published: Faculty of Pharmacy, Cairo University 2014-12-01
Series:Bulletin of Faculty of Pharmacy Cairo University
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110093114000337