REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis
Abstract REV1 is the central member of the family of TLS polymerases, which participate in various DNA damage repair and tolerance pathways and play a significant role in maintaining genomic stability. However, the role of REV1 in tumors is rarely reported. In this study, we found that the expressio...
Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Nature Publishing Group
2022-02-01
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Σειρά: | Cell Death and Disease |
Διαθέσιμο Online: | https://doi.org/10.1038/s41419-022-04567-5 |