REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis

REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis

Abstract REV1 is the central member of the family of TLS polymerases, which participate in various DNA damage repair and tolerance pathways and play a significant role in maintaining genomic stability. However, the role of REV1 in tumors is rarely reported. In this study, we found that the expressio...

Full description

Bibliographic Details
Main Authors: Yunshang Chen, Xiaohua Jie, Biyuan Xing, Zilong Wu, Xijie Yang, Xinrui Rao, Yingzhuo Xu, Dong Zhou, Xiaorong Dong, Tao Zhang, Kunyu Yang, Zhenyu Li, Gang Wu
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04567-5

Internet

https://doi.org/10.1038/s41419-022-04567-5

Similar Items