REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis

Abstract REV1 is the central member of the family of TLS polymerases, which participate in various DNA damage repair and tolerance pathways and play a significant role in maintaining genomic stability. However, the role of REV1 in tumors is rarely reported. In this study, we found that the expressio...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Yunshang Chen, Xiaohua Jie, Biyuan Xing, Zilong Wu, Xijie Yang, Xinrui Rao, Yingzhuo Xu, Dong Zhou, Xiaorong Dong, Tao Zhang, Kunyu Yang, Zhenyu Li, Gang Wu
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Nature Publishing Group 2022-02-01
Σειρά:Cell Death and Disease
Διαθέσιμο Online:https://doi.org/10.1038/s41419-022-04567-5