Wingless-related integration site (WNT) signaling is activated during the inflammatory response upon cardiac surgery: A translational study

Wingless-related integration site (WNT) signaling is activated during the inflammatory response upon cardiac surgery: A translational study

ObjectiveCardiac surgery and the use of cardiopulmonary bypass initiate a systemic inflammatory response. Wingless-related integration site (WNT) signaling is part of the innate immunity and has been attributed a major role in the regulation of inflammation. In preclinical research, WNT-5a may susta...

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Bibliographic Details
Main Authors: Bernard D. Krüger, Gilles E. Hofer, Alain Rudiger, Gabriela H. Spahn, Julia Braun, Dominique Bettex, Gabriele Schoedon, Donat R. Spahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
inflammation
cardiac surgery
cardiopulmonary bypass
systemic inflammatory response syndrome
SIRS
WNT signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.997350/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.997350/full

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