The multiple actions of dipeptidyl peptidase 4 (DPP-4) and its pharmacological inhibition on bone metabolism: a review

Abstract Background Dipeptidyl peptidase 4 (DPP-4) plays a crucial role in breaking down various substrates. It also has effects on the insulin signaling pathway, contributing to insulin resistance, and involvement in inflammatory processes like obesity and type 2 diabetes mellitus. Emerging effects...

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Bibliographic Details
Main Authors: L. M. Pechmann, F. I. Pinheiro, V. F. C. Andrade, C. A. Moreira
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-024-01412-x