Proteomic Analysis of Brain Region and Sex-Specific Synaptic Protein Expression in the Adult Mouse Brain

Proteomic Analysis of Brain Region and Sex-Specific Synaptic Protein Expression in the Adult Mouse Brain

Genetic disruption of synaptic proteins results in a whole variety of human neuropsychiatric disorders including intellectual disability, schizophrenia or autism spectrum disorder (ASD). In a wide range of these so-called synaptopathies a sex bias in prevalence and clinical course has been reported....

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Bibliographic Details
Main Authors: Ute Distler, Sven Schumann, Hans-Georg Kesseler, Rainer Pielot, Karl-Heinz Smalla, Malte Sielaff, Michael J Schmeisser, Stefan Tenzer
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
mass spectrometry-based proteomics
synapse
sex
hippocampus
striatum
prefrontal cortex
cerebellum
autism spectrum disorder (asd)
ddx3x
set
Online Access:https://www.mdpi.com/2073-4409/9/2/313

Internet

https://www.mdpi.com/2073-4409/9/2/313

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