Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent

Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent

ABSTRACT Although viruses and viral capsids induce rapid immune responses, little is known about viral pathogen-associated molecular patterns (PAMPs) that are exhibited on their surface. Here, we demonstrate that the repeating protein subunit pattern common to most virus capsids is a molecular patte...

Full description

Bibliographic Details
Main Authors: Kelly M. Shepardson, Benjamin Schwarz, Kyle Larson, Rachelle V. Morton, John Avera, Kimberly McCoy, Alayna Caffrey, Ann Harmsen, Trevor Douglas, Agnieszka Rynda-Apple
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mBio
Subjects:
pattern recognition
bacterial superinfection
innate immunity
Toll-like receptors
virology
virus-host interactions
Online Access:https://journals.asm.org/doi/10.1128/mBio.01356-17

Internet

https://journals.asm.org/doi/10.1128/mBio.01356-17

Similar Items