Lysosomal destabilization: A missing link between pathological calcification and osteoarthritis

Lysosomal destabilization: A missing link between pathological calcification and osteoarthritis

Calcification of cartilage by hydroxyapatite is a hallmark of osteoarthritis and its deposition strongly correlates with the severity of osteoarthritis. However, no effective strategies are available to date on the prevention of hydroxyapatite deposition within the osteoarthritic cartilage and its r...

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Bibliographic Details
Main Authors: Tao Ye, Chenyu Wang, Jianfei Yan, Zixuan Qin, Wenpin Qin, Yuxuan Ma, Qianqian Wan, Weicheng Lu, Mian Zhang, Franklin R. Tay, Kai Jiao, Lina Niu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-04-01
Series:Bioactive Materials
Subjects:
Osteoarthritis
Hydroxyapatite
Lysosomal destabilization
Chondrocyte pyroptosis
Pathological calcification
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23003973

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http://www.sciencedirect.com/science/article/pii/S2452199X23003973

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