Expression Analysis of Ligand-Receptor Pairs Identifies Cell-to-Cell Crosstalk between Macrophages and Tumor Cells in Lung Adenocarcinoma

Background. Lung adenocarcinoma is one of the most commonly diagnosed malignancies worldwide. Macrophage plays crucial roles in the tumor microenvironment, but its autocrine network and communications with tumor cell are still unclear. Methods. We acquired single-cell RNA sequencing (scRNA-seq) (n=3...

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Bibliographic Details
Main Authors: Xiaodong Yang, Zhao An, Zhengyang Hu, Junjie Xi, Chenyang Dai, Yuming Zhu
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2022/9589895