Design, multistep synthesis and in-vitro antimicrobial and antioxidant screening of coumarin clubbed chalcone hybrids through molecular hybridization approach

Design, multistep synthesis and in-vitro antimicrobial and antioxidant screening of coumarin clubbed chalcone hybrids through molecular hybridization approach

In the present study we designed and synthesized 26 coumarin clubbed chalcone hybrids (1–13 and 14–26) in good yields (54.32–74.25%) and further tested for their antimicrobial and antioxidant activities considering the potential bioactivities of these two pharmacophores. All Spectroscopic techniques...

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Bibliographic Details
Main Authors: Sathish Kumar Konidala, Vijay Kotra, Ravi Chandra Sekhara Reddy Danduga, Phani Kumar Kola, Richie R. Bhandare, Afzal B. Shaik
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Arabian Journal of Chemistry
Subjects:
Coumarin
Chalcone
Coumarin clubbed chalcone
Hybrids
Antimicrobial
Antioxidant
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221001696

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http://www.sciencedirect.com/science/article/pii/S1878535221001696

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