Role of cell migration in the pathogenesis of rheumatoid arthritis: in vivo studies in SCID mice transplanted with human synovial membrane

Objective: adhesion mechanisms play a central role in the recruitment of leukocytes which characteristically infiltrate rheumatoid synovium. Therefore, we adapted an animal model, in which human rheumatoid synovium was transplanted into severe combined immunodeficient (SCID) mice, to study the effec...

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Bibliographic Details
Main Authors: F. Ingegnoli, M. Blades, A. Manzo, S. Wahid, M. Perretti, G. Panay, C. Pitzalis
Format: Article
Language:English
Published: PAGEPress Publications 2002-06-01
Series:Reumatismo
Online Access:https://reumatismo.org/index.php/reuma/article/view/67