Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

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Neural stem cells (NSCs) divide asymmetrically to balance their self-renewal and differentiation, an imbalance in which can lead to NSC overgrowth and tumor formation. The functions of Parafibromin, a conserved tumor suppressor, in the nervous system are not established. Here, we demonstrate that Dr...

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Bibliographic Details
Main Authors: Qiannan Deng, Cheng Wang, Chwee Tat Koe, Jan Peter Heinen, Ye Sing Tan, Song Li, Cayetano Gonzalez, Wing-Kin Sung, Hongyan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555638/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555638/?tool=EBI

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