Exercise improves behavioral dysfunction and inhibits the spontaneous excitatory postsynaptic current of D2-medium spiny neurons

The abnormal function of striatal medium spiny neurons (MSNs) leads to the excitation-inhibition imbalance of the basal ganglia, which is an important pathogenic factor of Parkinson’s disease (PD). Exercise improves the dysfunction of basal ganglia through neuroprotective and neuroreparative effects...

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Bibliographic Details
Main Authors: Gang Zhao, Danyu Zhang, Decai Qiao, Xiaoli Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1001256/full