The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy

The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy

Abstract Background Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal insufficiency. Enhanced intracellular conversion of inactive cortisone t...

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Bibliographic Details
Main Authors: Rosemary Dineen, Lucy-Ann Behan, Grainne Kelleher, Mark J. Hannon, Jennifer J. Brady, Bairbre Rogers, Brian G. Keevil, William Tormey, Diarmuid Smith, Christopher J. Thompson, Malachi J. McKenna, Wiebke Arlt, Paul M. Stewart, Amar Agha, Mark Sherlock
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Endocrine Disorders
Subjects:
Cortisone
Cortisol
Bone turnover markers
Hypopituitarism
Metabolites
Adrenal insufficiency
Online Access:http://link.springer.com/article/10.1186/s12902-020-00633-1

Internet

http://link.springer.com/article/10.1186/s12902-020-00633-1

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