The expression pattern of GDF15 in human brain changes during aging and in Alzheimer’s disease

The expression pattern of GDF15 in human brain changes during aging and in Alzheimer’s disease

IntroductionGrowth Differentiation Factor 15 (GDF15) is a mitochondrial-stress-responsive molecule whose expression strongly increases with aging and age-related diseases. However, its role in neurodegenerative diseases, including Alzheimer’s disease (AD), is still debated.MethodsWe have characteriz...

Полное описание

Библиографические подробности
Главные авторы: Antonio Chiariello, Sabrina Valente, Gianandrea Pasquinelli, Alessandra Baracca, Gianluca Sgarbi, Giancarlo Solaini, Valentina Medici, Valentina Fantini, Tino Emanuele Poloni, Monica Tognocchi, Marina Arcaro, Daniela Galimberti, Claudio Franceschi, Miriam Capri, Stefano Salvioli, Maria Conte
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2023-01-01
Серии:Frontiers in Aging Neuroscience
Предметы:
GDF15
Alzheimer’s disease
aging
inflammation
mitochondrial dysfunction
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1058665/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.1058665/full

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