Fucoidan-Mediated Inhibition of Fibrotic Properties in Oral Submucous Fibrosis via the MEG3/miR-181a/Egr1 Axis

Fucoidan-Mediated Inhibition of Fibrotic Properties in Oral Submucous Fibrosis via the MEG3/miR-181a/Egr1 Axis

Oral submucous fibrosis (OSF) is a chronic fibrotic remodeling disease that can progress to oral cancer. However, efficient clinical diagnosis and treatment methods for OSF are still lacking. This study investigated the anti-fibrotic effect of fucoidan on oral fibrosis. To evaluate the fibrotic abil...

Full description

Bibliographic Details
Main Authors: Chih-Yuan Fang, Szu-Han Chen, Chun-Chung Huang, Yi-Wen Liao, Shih-Chi Chao, Cheng-Chia Yu
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceuticals
Subjects:
oral submucous fibrosis
MEG3
miR-181a
Egr1
myofibroblasts
competing endogenous RNA
Online Access:https://www.mdpi.com/1424-8247/15/7/833

Internet

https://www.mdpi.com/1424-8247/15/7/833

Similar Items