Allogeneic Hematopoietic Stem Cell Transplantation After Prior Lung Transplantation for Hereditary Pulmonary Alveolar Proteinosis: A Case Report

Allogeneic Hematopoietic Stem Cell Transplantation After Prior Lung Transplantation for Hereditary Pulmonary Alveolar Proteinosis: A Case Report

Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disorder characterized by surfactant accumulation in the small airways due to defective clearance by alveolar macrophages, resulting in impaired gas exchange. Whole lung lavage is the current standard of care treatment for PAP. Lung transp...

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Bibliographic Details
Main Authors: Hanne Beeckmans, Gene P. L. Ambrocio, Saskia Bos, Astrid Vermaut, Vincent Geudens, Arno Vanstapel, Bart M. Vanaudenaerde, Frans De Baets, Thomas L. A. Malfait, Marie-Paule Emonds, Dirk E. Van Raemdonck, Hélène M. Schoemans, Robin Vos, for the Leuven Lung Transplant Group, Laurens J. Ceulemans, Geert M. Verleden, Lieven J. Dupont, Laurent Godinas, Veronique Schaevers, Dirk Claes, Karen Denaux, Bruno Desschans, Liesbeth Daniëls, Eric K. Verbeken, Birgit Weynand, Johny Verschakelen, Adriana Dubbeldam, Renata Haghedooren
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
pulmonary alveolar proteinosis
lung transplantation
bone marrow transplantation
allogeneic hematopoietic stem cell transplantation
rejection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.931153/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.931153/full

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