A gene network perspective on axonal regeneration

The regenerative capacity of injured neurons in the central nervous system is limited due to the absence of a robust neuron-intrinsic injury-induced gene response that supports axon regeneration. In peripheral neurons axotomy induces a large cohort of regeneration-associated genes (RAGs). The force...

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Bibliographic Details
Main Authors: Ronald E. Van Kesteren, Matthew R.J. Mason, Harold D. MacGillavry, August B Smit, Joost eVerhaagen
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00046/full