In-silico identification of novel natural drug leads against the Ebola virus VP40 protein: A promising approach for developing new antiviral therapeutics

In-silico identification of novel natural drug leads against the Ebola virus VP40 protein: A promising approach for developing new antiviral therapeutics

Ebola, one of the deadliest known infectious diseases, was the root of epidemics in Western Africa from 2013 to 2016. Like other deadly viruses in the family Filoviridae with a high fatality rate, this virus also causes hemorrhagic fever. As a result, the Ebola virus (EBOV) represents a threat to gl...

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Bibliographic Details
Main Authors: Noimul Hasan Siddiquee, Md Ifteker Hossain, Md Enamul Kabir Talukder, Syed Afnan Arefin Nirob, Md Shourav, Israt Jahan, Umme Habiba Akter Tamanna, Pinky Das, Rahima Akter, Mahmudul Hasan, Md Abdullah-Al-Mamun, Otun Saha
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Informatics in Medicine Unlocked
Subjects:
In-silico drug design
Ebola virus VP40 protein
Pharmacokinetics [ADME] and toxicity
Molecular docking
Post docking MM-GBSA
MD simulation and PCA
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914824000145

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http://www.sciencedirect.com/science/article/pii/S2352914824000145

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