Computational Analysis Reveals Unique Binding Patterns of Oxygenated and Deoxygenated Myoglobin to the Outer Mitochondrial Membrane

Computational Analysis Reveals Unique Binding Patterns of Oxygenated and Deoxygenated Myoglobin to the Outer Mitochondrial Membrane

Myoglobin (Mb) interaction with the outer mitochondrial membrane (OMM) promotes oxygen (O<sub>2</sub>) release. However, comprehensive molecular details on specific contact regions of the OMM with oxygenated (oxy-) and deoxygenated (deoxy-)Mb are missing. We used molecular dynamics (MD)...

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Bibliographic Details
Main Authors: Andriy Anishkin, Kiran Kumar Adepu, Dipendra Bhandari, Sean H. Adams, Sree V. Chintapalli
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomolecules
Subjects:
myoglobin
mitochondria
diffusion
Online Access:https://www.mdpi.com/2218-273X/13/7/1138

Internet

https://www.mdpi.com/2218-273X/13/7/1138

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