Analysis of Upstream Regulators, Networks, and Pathways Associated With the Expression Patterns of Polycystic Ovary Syndrome Candidate Genes During Fetal Ovary Development

Analysis of Upstream Regulators, Networks, and Pathways Associated With the Expression Patterns of Polycystic Ovary Syndrome Candidate Genes During Fetal Ovary Development

Polycystic Ovary Syndrome (PCOS) is a multifactorial syndrome with reproductive, endocrine, and metabolic symptoms, affecting about 10% women of reproductive age. Pathogenesis of the syndrome is poorly understood with genetic and fetal origins being the focus of the conundrum. Genetic predisposition...

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Bibliographic Details
Main Authors: Rafiatu Azumah, Katja Hummitzsch, Monica D. Hartanti, Justin C. St. John, Richard A. Anderson, Raymond J. Rodgers
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Genetics
Subjects:
polycystic ovary syndrome
mitochondrial dysfunction
stromal expansion
steroidogenesis
upstream regulators
fetal ovary
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.762177/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.762177/full

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