A Moraxella Virulence Factor Catalyzes an Essential Esterase Reaction of Biotin Biosynthesis

A Moraxella Virulence Factor Catalyzes an Essential Esterase Reaction of Biotin Biosynthesis

Pimeloyl-acyl carrier protein (ACP) methyl ester esterase catalyzes the last biosynthetic step of the pimelate moiety of biotin, a key intermediate in biotin biosynthesis. The paradigm pimeloyl-ACP methyl ester esterase is the BioH protein of Escherichia coli that hydrolyses the ester bond of pimelo...

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Bibliographic Details
Main Authors: Qi Zeng, Qi Yang, Jia Jia, Hongkai Bi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Microbiology
Subjects:
Moraxella catarrhalis
methyl esterase
pimelate thioester
biotin synthetic pathway
bacterial virulence
BtsA
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00148/full

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https://www.frontiersin.org/article/10.3389/fmicb.2020.00148/full

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