Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors

Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors

During resolution of inflammation, specialized proresolving mediators (SPMs), including resolvins, are produced to restore tissue homeostasis. We hypothesized that there might be a dysregulation of SPMs pathways in pathological vascular remodeling and that resolvin D2 (RvD2) might prevent vascular r...

Full description

Bibliographic Details
Main Authors: Raquel Rodrigues-Diez, Constanza Ballesteros-Martinez, Rosa María Moreno-Carriles, Francisco Nistal, Lucía S. Díaz del Campo, Victoria Cachofeiro, Jesmond Dalli, Ana B. García-Redondo, Juan M. Redondo, Mercedes Salaices, Ana M. Briones
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Resolvin D2
vascular remodeling
Endothelial dysfunction
Hypertension
Obesity
Resolution of inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224004487

Internet

http://www.sciencedirect.com/science/article/pii/S0753332224004487

Similar Items