Engineering an Enhanced EGFR Engager: Humanization of Cetuximab for Improved Developability
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase whose proliferative effects can contribute to the development of many types of solid tumors when overexpressed. For this reason, EGFR inhibitors such as cetuximab can play an important role in treating cancers such as colorect...
| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
MDPI AG
2022-01-01
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| coleção: | Antibodies |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2073-4468/11/1/6 |